Unlike ELR+ chemokines, the ELR− group represents the major chemoattractants for mononuclear cells including CXCL9/Mig, CXCL10/IP-10, and CXCL11/I-TAC, all upregulated during early IPA [126, 145]. Here, CXCL10 is linked to Ito hypomelanosis.