Velmurugan et al. [75] demonstrated that the combination of S-allylcysteine, an organosulfur constituent of garlic, and lycopene was more effective in suppressing the development of N-methyl-N′-nitro-N′-nitroso-guanidine- (MNNG-) induced gastric cancer through diminution of Bcl-2 expression and increase of Bax, Bim, and caspase 8 expression that either agent alone; furthermore, the induction of apoptosis was achieved at half the dose reported by previous studies [110]. The gene discussed is CASP8; the disease is gastric cancer.