CD4 and allergic disease: It has been shown that expression of mRNA for cytokines associated with lymphocytes Th2 (especially IL-5) and the concentration of these cytokines in the tissues of an allergic reaction correlate with the number of excited eosinophil's purposes [34, 35] which indicates that the accumulation and activation of lymphocytes CD4+ T cells are directly related to the induction of eosinophilic infiltration.