Collectively, these data indicate that while malnutrition selectively reduced the number or percentage of FRCs and several myeloid cell populations in the LN (resident and/or migratory DCs, MOMA2+ and CD169+ macrophages), it did not alter the localization of the FRCs or different phagocyte populations in the LN with the exception of reduced numbers of CD169+ macrophages in the sub-cortical region. The gene discussed is SIGLEC1; the disease is nutritional deficiency disease.