Notably, for Mts-2 QTL on chromosome-1, the marker at the QTL-peak, D1Rat350, is located within the Anpep [alanyl (membrane) aminopeptidase] transcription unit, an enzyme that might be a candidate gene because it has been associated with invasive colorectal cancer [30] and prostate cancer [31], and Barrett’s adenocarcinoma [32]. The gene discussed is ANPEP; the disease is Familial prostate cancer.