Furthermore, expression and secretion of CCL-2, CCL-5 and CX3CL-1 by human coronary artery endothelial cells as well as monocytes was inhibited by preincubation with rHDL [43], and rHDL (CSL111; 80 mg/kg) infused in patients with peripheral vascular disease decreased CD11b on neutrophils [44]. Here, ITGAM is linked to peripheral vascular disease.