In the analysis of BD association and psychosis association, the most significant association maps to the Sp8 transcription factor (SP8) locus (rs2709736: uncorrected P = 0.0055 for BD, and rs2709722, uncorrected P = 0.0010 for psychosis), which is the same direction as the original Taiwanese population-based study [16]. This evidence concerns the gene SP8 and psychotic disorder.