CTA095 has little effect on the survival of the immortalized normal prostate cell RWPE1, suggesting that the growth and survival of prostate cancer cells are more dependent on Etk and Src signals, consistent with the observed overexpression of Etk in prostate cancer tissues and the development of PIN phenotype in transgenic animals carrying overexpressed Etk [11]. This evidence concerns the gene SRC and prostate intraepithelial neoplasia.