In Table 3, rs1051055 (CDC123), rs699780 (NOTCH2), and rs2688 (TCF2) interacted with arsenic in drinking water to significantly increase the risk of T2DM with p-values for the SNP-arsenic interactions as 0.008, 0.003, and 0.003, respectively. Here, NOTCH2 is linked to type 2 diabetes mellitus.