NRG1 and schizophrenia: It should be noted that sex-specificity in rodent models for Nrg1 is a common phenomenon (O'Tuathaigh et al., 2006; Duffy et al., 2010; Chesworth et al., 2012a) and is in line with gender effects reported for schizophrenia patients (Canuso and Pandina, 2007).