Several mantle cell lymphoma lines, including Granta-519, HBL-2, JEKO-1 and JVM-2, exhibited TCF/LEF reporter levels as high or higher than Ramos (Figure S1E) and also contained undetectable levels of uncomplexed β-catenin (Figure S1F), implying their activation of β-catenin-independent TCF/LEF transcriptional activity. The gene discussed is HNF4A; the disease is mantle cell lymphoma.