IL2 and metastatic malignant neoplasm: Notably, human Vγ2Vδ2 T cells can be selectively expanded in vivo by zoledronate, a clinical drug widely used for treatment of bone-related disease, and that zoledronate/IL-2 expansion of Vγ2Vδ2 T cells has been tested as therapeutic regimen for treatment of metastatic cancers [18], [19].