To study the mechanism of miR-143 regulation in allergic inflammation, we investigated the target genes of miR-143 through the TargetScan procedure (http://genes.mit.edu/tscan/targetscanS.html and http://pictar.mdc-berlin.de/) to predict miR-143 target genes, and found that the IL-13Rα1 gene 3′ UTR had 15 sequential pairing bases with miR-143 (Table 1), which indicates that IL-13Rα1, known to play an important role in allergy, may be a potential target of miR-143. This evidence concerns the gene IL13RA1 and allergic disease.