The possible tumor suppressor-like function of H19 was derived from the observed tumor growth inhibition resulting from the H19 cDNA transfection of G401-transformed kidney cells and the fact that H19 serves as a precursor of microRNA-675 (miR-675) that targets insulin-like growth factor 1 receptor (IGF1R) [24, 25]. Here, H19 is linked to neoplasm.