CYP2B6 and AIDS: Human cytochrome P450 2B6 (CYP2B6) is involved in the biotransformation of a variety of clinically important drugs such as the antiretroviral nevirapine (NVP) and efavirenz (EFV), which are used to treat AIDS and/or stop the spread of HIV infection (Erickson et al. 1999; Ward et al. 2003), antimalarial drug artemisinin (Simonsson et al. 2003; Mehlotra et al. 2006) and other drugs including cyclophosphamide, tamoxifen, diazepam, and bupropion (Lang et al. 2001; Wang and Thompkins 2008).