Peptide mass finger printing using MALDI-TOF revealed sequence similarity of purified SAF to glutamate decarboxylase and that of receptor to MHC class I. Interaction between the two molecules has already been reported in case of diabetes mellitus where MHC class I restricted determinants have been found on glutamic acid decarboxylase 65 molecule capable of inducing spontaneous CTL activity [14]. This evidence concerns the gene GLUL and diabetes mellitus.