LC-HR patients did not demonstrate normalized TREC levels compared to LC patients, and similarly, we found no significant differences, neither in the proportion of mucosal T cells expressing Ki67 and the active/memory marker CD45RO nor mucosal mRNA and protein expression of effector T cell cytokines compared to LC patients with histopathologically active disease [16, 26], suggesting that mucosal T cell responses in LC-HR patients are as active as in LC patients. The gene discussed is MKI67; the disease is laryngotracheoesophageal cleft.