Previous studies have suggested an association of SYN2 rs3773364 A>G polymorphism with febrile seizures in the UK, Irish and Finnish cohorts [EPIGEN Epilepsy Genetic Consortium; (47)] and in Indian patients with idiopathic epilepsy (48), but not in the Australian cohort (47) or in Malaysian epileptic patients (59). This evidence concerns the gene SYN2 and epilepsy.