The region located between 3p21.3 and 3p14.3, deleted in both cell sub-lines, contains several established tumor suppressor genes including LTF, TDGF1, WNT5a, and RASSF (37), as well as candidate tumor suppressors such as CACNA2D3, GNAI2, and SEMA3B. This evidence concerns the gene WNT5A and neoplasm.