Among the genes that had only little association with DS before we found FBN1 which was predominantly upregulated in the studies under analysis (in 80% of the expression studies; upregulated in 4 out of 5 human studies and in 3 out of 5 DS mouse models (from the ones with a detection P-value <0.1; Fig. 1A). The gene discussed is FBN1; the disease is Dravet syndrome.