Remarkable is this last result highlighting genes like MMP2, COL1A1 and COL1A2 previously validated by PCR in the DS heart study from Conti et al. (Conti et al., 2007) and FBN1, DCN, COL1A2, COL1A1 and COL3A1 significant in the meta-analysis and cross-validated in the DS heart study (Conti et al., 2007) through the Bayesian approach. This evidence concerns the gene COL1A2 and Dravet syndrome.