Studies on relationships between induction of apoptosis in prostate cancer cells and expression of Bcl-2 and Bax-related proteins gave contradictory results [16–21], and the data suggest that Bcl-2, Bcl-xL and some other apoptosis-related proteins are not important for induction of apoptosis in prostate cancer cells [18,19,22–24]. This evidence concerns the gene FAM215A and Familial prostate cancer.