Seven genes overexpressed in Iqgap2−/− HCC tumors were related to hepatic steatosis – Acsl4, Ccnd1, CD44, Fabp5, Lpl, Pdgfc and Pparg. Again, this is in agreement with reported earlier aberrations in fatty acid uptake and lipogenesis in Iqgap2−/− livers [21]. This evidence concerns the gene CCND1 and Hepatic steatosis.