SMO and medulloblastoma: Using the Smo/Smo medulloblastoma mouse model, we analyzed the expression patterns of HDACs 1 through 11 and found increased expression and activity of HDACs 1, 2, and 6 in medulloblastoma tumors when compared to wild-type cerebellum or cerebellum from Smo/Smo mice that did not develop tumors.