Concerning SNP rs3824872, located in the 3′ region of CRY2 (but also in the 5′ region of MAPK8IP1 gene), our study suggests (q = 0.08) that the T allele is the protective one against dysthymia, and a similar (though non-significant) tendency is seen in the Finnish subpopulation of the winter depression study [24], while in the Swedish subpopulation of the same study, the other allele, i.e. A, was the risk allele. The gene discussed is MAPK8IP1; the disease is dysthymic disorder.