Molecular markers relevant for GBM such as the methylation status of the MGMT promoter, the amplification rate of EGFR, as well as mutation status of the genes IDH 1 and 2, TP53, K-Ras and B-Raf were assessed for the cell line pairs in comparison to the original tumor material (Table 4). The gene discussed is EGFR; the disease is neoplasm.