However, the levels of cSrc (figure 7c) were significantly elevated in chronic HCV (3.2 ± 0.4) and NASH (2.4 ± 0.7) but not in HCV infected liver with no fibrosis (1.7 ± 1.1).These results demonstrate that HCV infection leads to a significant modulation of the miRNA profile that promotes development of fibrosis following chronic HCV infection. This evidence concerns the gene SRC and metabolic dysfunction-associated steatohepatitis.