MYD88 and myeloid sarcoma: To investigate whether regulation of TLRs in vitro is paralleled by similar changes in interferon-β-treated patients with MS we analyzed a data set from 25 patients with RRMS before and one month after start of treatment with interferon-β-1b [10], [11] for gene expression levels of TLR1-10, MyD88, and MX1.