Although PBMCs of Sal-Ag induced significantly lower level of IFN-γ than MAP316F, the level was significantly higher than PBS and vector controls at week 6, 10 and 14 which correlated well with partial protection as increased expression of this cytokine is observed during early stage of infection and reduction in its level is the hallmark of clinical JD [37], [38]. Here, IFNG is linked to infection.