Taken together, as Vδ1+ T cells are known to recognize NKG2D ligands as a mechanism for cytotoxic activity, these findings suggest that the extent to which different glioma cell lines regulate NKG2DL expression in response to CMV infection is variable and may be associated with partial protection from Vδ1+ T cell – mediated lysis. Here, KLRK1 is linked to cytomegalovirus infection.