GPT and obesity due to melanocortin 4 receptor deficiency: Although obesity has been described as a potential risk factor, a retrospective Canadian study of children < 18 years of age found that, compared to those with established type 2 diabetes, those with medication-induced diabetes were less likely to be obese, have a positive family history of type 2 diabetes, and have obesity-related comorbidities (e.g., dyslipidemia, hypertension or elevated alanine aminotransferase levels) [97].