KDR and ovarian neoplasm: Furthermore, it was also revealed that the MVD of the patients with positive KDR expression was 21.64±8.63, significantly higher than that of the KDR-positive patients (17.06±7.87; P=0.035), while there was no significant difference in the mean MVD between the patients with and without Flt-1 expression, indicating that VEGF promotes ovarian tumor angiogenesis mainly by interacting with KDR.