For example, the overexpression of heterogeneous nuclear ribonucleoprotein H (hnRNP H) has been shown to partially counteract apoptosis induced by etoposide, and also to block mammalian STE20-like protein kinase 2 (MST2; proapoptotic MST2 kinase)-mediated apoptosis in cancer cells (45). The gene discussed is HNRNPH2; the disease is cancer.