To test the hypothesis that TERT and AP-1 are overexpressed in laryngeal carcinoma cells and therefore could contribute to laryngeal carcinoma cell proliferation, we analyzed the mRNA and protein expression levels of TERT, c-Fos and c-Jun in HEp-2 cells and human laryngeal carcinoma tissue samples. The gene discussed is FOSB; the disease is laryngeal carcinoma.