Kuramoto investigated the expression of the MAGE-A1 and -A4 proteins in 28 brain tumor tissues (14 gliomas and 14 non-gliomas) by immunoblot analysis and observed positive results in the majority of gliomas (12 of 14) and a few (5 of 14) non-gliomas (12). The gene discussed is MAGEA1; the disease is central nervous system cancer.