GSK3B and cancer: GSK3β inhibitor VIII, on the other hand, exhibited modest cell toxicity on EM-TERT cells at 10 μM (7.7% ± 3.6% vs. 2.4% ± 1.1%), but caused significant cell death in both cancer cell lines (66.5% ± 2.9% vs. 3.1% ± 1.4% in AN3CA; 14.4% ± 3.1% vs. 2.2% ± 0.2% in ARK1, Figure S2).