An up-to-date study by Simon T et al. [16] found that elevated levels of IL-17 are associated with a better outcome in patients with acute myocardial infarction, supporting a protective regulatory role of IL-17 in coronary heart disease,whereas IL-6 levels were associated with a worse outcome despite the fact that IL-6 and IL-17 might induce each other. Here, IL17A is linked to acute myocardial infarction.