IGHG3 and infection: Although there were higher levels of anti- S. aureus IgG1, IgG2 and IgG3 antibodies in the suspected group, they were independently associated with a reduced risk of EOS infection [OR = 0.30; 95% CI = (0.12-0.76), P value < 0.011], [For medium level of IgG2; OR = 0.44; 95% CI = (0.37-0.73), P value = 0.001 and for higher level of IgG2 OR = 0.34; 95% CI = (0.20-0.49), P value = 0.030] and [OR = 0.32; 95% CI = (0.13-0.75), P value = 0.009] respectively (Table 6).