MTOR and neoplasm: Nevertheless, the associations between mTOR rs2536 C variant or genotypes and cancer risk in Chinese populations were various in the literatures; for example, the mTOR rs2536 CT heterozygous genotype was found to be associated with decreased risk of Chinese childhood acute lymphoblastic leukemia [28]; however, this association was not observed in other tumor types, such as gastric cancer [29], prostate cancer [24], and esophageal squamous cell carcinoma [30].