Interestingly, Api5 expression is deregulated in multiple cancer cell lines, including various human cancers: cervical or prostate, Non Small Cell Lung Cancer (NSCLC), and B cell chronic lymphoid leukemia (B-CLL) [23], [26], [25], [27], [28], [22], [29], [24], [30]. Here, API5 is linked to B-cell chronic lymphocytic leukemia.