After controlling for Mb, SMR did not show differences between populations (Fig. 6; Table 3), but BD showed significant differences (Fig. 6; Table 3), explained by a greater ability to maintain water balance (i.e., lower % body dehydration) in Valdivia compared to the other two populations (Fig. 3, Tukey’s HSD tests, P = 0.02). The gene discussed is MB; the disease is Behcet disease.