The top 50 over-abundant differentially expressed transcripts for each disease correlated with the findings from the modular and IPA analysis where TB and active sarcoidosis were dominated by IFN-inducible genes e.g. IFITM3, IFIT3, GBP1, GBP6, CXCL10, OAS1, STAT1, IFI44L, FCGR1B (Table S5). The gene discussed is GBP1; the disease is tuberculosis.