GBM Module 2 contained 10 CGC genes of TP53, BRCA1, BRCA2, DAXX, DDX5, MDM2, MDM4, NPM1, TEP1, and WRN, resulting in a -value of 1.0510, and 2 GBM-related genes of TP53 and TEP1, resulting in a -value of 1.0210. The gene discussed is MDM4; the disease is glioblastoma.