TCF7L2 and colorectal cancer: The Cancer Genome Atlas Network recently performed exome capture DNA sequencing of colorectal cancers and identified frequently mutated genes including APC, TP53, KRAS, PIK3CA, FBXW7, SMAD4, TCF7L2, NRAS, ARID1A, SOX9 and FAM123B (WTX) genes [14].