In the DNA binding group we find three DNA repair enzymes, one in the mismatch repair (MMR) pathway, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (mlh1, GB17468) and one in the nucleotide excision repair (NER) pathway, xeroderma pigmentosum group A-like (xpac, GB14782). The gene discussed is MLH1; the disease is colonic neoplasm.