MTHFD1 and acute lymphoblastic leukemia: According to the BN-BMLA the probability that rs2236225 and rs745686 in the MTHFD1 gene were associated to ALL susceptibility was 0.71, but their probabilities of strong relevance to ALL were nearly zero while the value of their transitive relevance was 0.61, meaning that this association is probably mediated by the direct relevance of rs1076991 in the MTHFD1 gene.