A recent report by Wild-Bode, C. et al [5] demonstrated that radiation-induced glioma invasiveness was associated with the synergistic interaction of the altered BCL-1/BAX rheostat, which favored the resistance of glioma cells to apoptosis and the increased expression of migration/invasion-associated genes, such as αvβ3 integrin, MMP-2, and MMP-9. This evidence concerns the gene MMP2 and glioma.