In this context, the “screen all RD genes” approach has certainly benefitted three of our cases, initially diagnosed as undefined RD (patient 10/1367), LCA (patient 04/0834), or RP (patient 07/0360), but having mutations in CNGB3 and CHM causing achromatopsia and choroideremia, respectively, that would be missed by ARRP or LCA genotyping microarray. The gene discussed is CHM; the disease is choroideremia.