Baseline factors associated with clinical failure by univariate analysis included US Centers for Disease Control and Prevention (CDC) stage B or C, anemia (hemoglobin ≤10 g/dl), CD4 count below median, i.e., 150 cells/mm3 (all p<0.001), VL above 5 log10 copies/ml (p = 0.001), and body mass index (BMI) below 18.5 (p = 0.002) (Table 4). This evidence concerns the gene CD4 and anemia (phenotype).