NES and myocardial infarction: By contrast, in the peri-infarct/infarct region of 4 day post-MI rat hearts, innervating nestin(+) fibres co-expressing neurofilament-M were observed and neurofilament-M/nestin(+) fibres persisted in the ischemic region of 7-day post-MI rat hearts (Figure 1C, D & E).