In the heart of 10-day post-MI rats, the reparative fibrotic response was associated with neurofilament-M(+) fibres (754 ± 126 μm2/mm2; n = 3) innervating the peri-infarct/infarct region and the majority co-expressed nestin (608 ± 79 μm2/mm2; n = 3) (Figure 3A, 3B &3C). The gene discussed is NES; the disease is myocardial infarction.