Furthermore, the GC cases were classified according to histological types, we found that 100% (6/6) in the MA or SRCC group were the phenotype of PGC-/MUC1-/MUC2+ (Figure 2 G-I), other phenotypes group in the MA or SRCC group were significantly lower compared with that of PGC-/MUC1-/MUC2+ phenotype group (P < 0.05, Table 3). This evidence concerns the gene MUC2 and gastric cancer.